The Benefits of Using SanPharma Isopathic Suppositories in Complementary Medicine

By:
Ronald Ullmann, biochemist, Symbio Systems, Germany
Michael Sheehan, BioResource Inc., Santa Rosa, California

@ Copyright 2001

Isopathic suppositories provide practitioners with a powerful healing tool, especially in the treatment of chronic illnesses. SanPharma of Germany produces both fungal and bacterial suppositories based on the research of Prof. Dr. Guenther Enderlein that offer patients the following benefits:

• Superior absorption into the body by avoiding the liver (first-pass effect) and digestive tract
  
• Dispersal of active substances throughout the body over an extended period of time
  
• Prevents overburdening of the liver and kidneys
  
• Most powerful form of isopathic fungal-based therapy

In addition, SanPharma offers isopathic-homeopathic suppositories made according to strict Good Manufacturing Practices (GMP) certification, a world-wide standard for quality that will become essential for pharmaceutical companies around the globe.

Why Use SanPharma Fungal Suppositories?
In the late 19th and early 20th centuries, researchers such as Bechamps, Villequez, Enderlein and others observed fundamental changes in the blood of patients suffering from various illnesses. Using microscopes and staining techniques, they reported that specific pathogenic structures developed in size and appearance depending on the type and progress of a particular illness. This observation led to the conclusion that a constant intoxification and high acidic load in the blood (which maintains a slightly alkaline pH) leads to ongoing physiological disturbances that can result in chronic illnesses.

SanPharma isopathic fungal-based remedies enable patients to overcome these disturbances. Produced in a powerful 3X potency, the suppositories are available in Aspergillus (niger) for paratubercular or connective tissue conditions and lymph circulation; Candida (parapsilosis) for mycotic infections; Mucor (racemosus) for all types of circulatory disturbances; Notatum (Pen. notatum) for bacterial infections; and a Candida-Roqueforti (Candida parapsilosis-Pen. roqueforti) combination for intestinal dysbacteria/yeast infections. The optimal time to take suppositories is at bedtime. During sleep, the self-healing activity of isopathic remedies can be utilized fully by the body for renewal and healing.

Although many patients may be reluctant at first to use suppositories, this medicinal form provides the most efficient -and cost-effective -way to deliver Enderlein therapy. The surface of the rectal mucosa is quite limited compared to the small and large intestine, yet it still offers a highly efficient mechanism to transport isopathic ingredients across the mucosal barrier. With such a small surface area through which to be absorbed, the active ingredients gradually enter the bloodstream over a long period of time in moderate concentrations, providing a gentle activation of the body's self-healing capabilities.

Another advantage of suppositories is that transport of active ingredients into the bloodstream occurs in a region of the rectum not connected to the portal vein. As a result, the active ingredients are not initially degraded by the liver, which allows more isopathic medicine to circulate throughout the body. In contrast to drops and capsules, therefore, suppositories avoid the liver and digestive tract (stomach, small and large intestine) on the first pass to deliver more active ingredients. Moreover, this "first pass effect" in small concentrations reduces stress on the liver and kidneys, which eventually must eliminate the pathological structures downgraded by SanPharma isopathic remedies.

The Need for Excretion Medications
Long-term clinical experience shows that SanPharma isopathic remedies work best when combined with excretion medications, such as PEKANA spagyrics, due to the release of substantial amounts of metabolic waste products into the bloodstream during the breakdown of complex morphological structures. These waste products must be processed by the liver and efficiently excreted from the body by the kidneys, skin and intestines. PEKANA medications help Drovide the DroDer milieu for successful elimination by helping the excretion organs function at peak performance.

Both laboratory and clinical testing have shown that SanPharma fungal suppositories are highly effective against acute and chronic illnesses. To avoid overreaction by the body, one to three fungal suppositories per week is normally sufficient.

Immune Regulation and SanPharma Bacterial Suppositories
To complement its fungal-based therapy I SanPharma also produces two bacterial suppositories : SanPharma Firmus 6X (Bacillus firm us) and Subtilis 6X (Bacillus subtilis). Both of these remedies are gentle immune modulators made from metabolic products designed to maximize the body's self-healing potential.

Importantly I SanPharma bacterial remedies -including Mycobactin S (Mycobacterium phlei) and Bacillus Cereus, which are available in capsule form -contain no cell wall fragments or killed bacteria. This eliminates the possibility of molecular mimicry I where the body develops antibodies against microbial protein structures that closely resemble different human tissues, potentially creating an auto-immune condition that has been reported in scientific papers for Mycobacteria, Candida albicans and other microorganisms. In addition, the success of fungal-based isopathic therapy can be dramatically enhanced by initially prescribing a SanPharma Subtilis 6X suppository I which supports the immune system on all levels of specific and non-specific response.

Intestinal Mucosa Plays Key Role
Why are bacterial suppositories so effective? Approximately 25 percent of the intestinal mucosa is comprised of gut-associated lymphoid tissue (GAL T) that plays a major role in the maintenance of health and recovery from many types of illnesses. Through a mechanism called colony resistance, the body regulates the normal (physiologic) microflora of the digestive tract. This microflora consists of two parts: the resident, which largely stays with the host organism, and the transient, which may dramatically change in composition without affecting the resident portion under normal physiological conditions. Although little is known about the biochemical mechanisms causing colony resistance, it has become evident that physicochemical properties such as pH-value, redox potential (ability to accept or give off electrons), oxygen to carbon dioxide ratio, temperature, nutrients and composition of the mucus play significant roles.

In addition to immunological barriers such as secretory Immunglobulins of Type A that reside in the mucus (known as antibody painting) , the physicochemical properties of the mucosa act as a regulative mechanism to prevent harmful molecules and microbes from settling down in the resident part of the mucosa, then entering the bloodstream. Scientific studies also have shown that the physiologic intestinal microflora perform immuno-triggering/immune- modulating functions. This can be best described as a constant exercising or training of the immune system to enable proper response to antigens and microorganisms that invade the human body.

This training mechanism works as follows: microfold cells that reside within the eoithelial cell laver of the intestinal mucosa serve as the channel of entry for molecules and particles into the underlying mucosa follicular region. This initiates an immune system modulation by, for example, activation of lymphocytes that enter the bloodstream and circulate throughout the entire body. Approximately 10 percent of the activated lymphocytes take up residence in the various mucosal layers (lung, mouth and nose), thereby transmitting the protective information to these regions, known as mucosa associated lymphoid tissue (MALT). The other 90 percent of the lymphocytes return to the intestinal lymphoid tissue (GAL T) in a process called homing.

Dealing with Dysbacteria
However, factors that distress the intestinal microflora, including impairment of liver and pancreatic function, poor nutrition, use of drugs and environmental toxins, can have a potent immunosupressive effect on systemic immunity by changing the physiologic composition of the micoroflora to a non-physiologic one that creates dysbacteria. Along with impairing the immune triggering function, dysbacteria is thought to be responsible for enhanced permeability of the mucosa. This condition enables various types of molecules and toxic substances that would normally be excreted to enter the bloodstream.

Together with impairment of the intestinal microflora's immune- triggering activities by dysbacteria, the enhanced permeability of the mucosa is mainly involved in immune function impairment. For example, it is known that enhanced permeability forces a downregulation of the immune system to prevent the body from developing an overreaction against the various molecules and toxic substances.

As a result, health care professionals need to focus their attention on eliminating low-grade chronic infections and inflammatory processes, which can be fertile grounds for malignant transformation. SanPharma Firmus and Subtilis bacterial suppositories provide an immune- modulating therapy that contributes significantly to this therapeutic success.

In summary, when used hand-in-hand with fungal-based remedies, Subtilis and Firmus suppositories increase the body's ability to heal itself. They also play an important role in recovery of a healthy immune status and establishing immune "painting" of secretory Ig A on all mucosa membranes, the body's first wall of protection. Finally, a therapy that combines both Subtilis and Firmus has proven highly effective for immune- modulation because each apparently addresses different immune-triggering activities.

Candida Infection Therapy: Combining Firmus, Subtilis and Candida-Roqueforti Suppositories
Treatment of Candida infections provides a clinically proven example of the therapeutic benefits derived from combining SanPharma Candida- Roqueforti 3X fungal suppositories with Firmus 6X and Subtilis 6X bacterial suppositories. Recommended dosage is one Subtilis suppository and one Firmus suppository per week Drescribed with two to three Candida- Roqueforti suppositories per week

Since mucosal inflammation and Candida infection often occur simultaneously, it is highly recommended to combine both immune regulation with anti-mycotic properties. This therapy enhances the recovery of the intestinal mucosa and microflora, while stimulating self- healing activity. To overcome a chronic Candida infection, a long-term therapy together with laboratory control of the stool is advised.

For more product information, contact BioResource at 800/203-3775.

@Copyright 2000 Symbio Systems and BioResource Inc.

Upcoming article from Symbio Systems and BioResource:

Enderlein Under The Microscope: A Modern. Scientific Look at Prof. Dr . Enderlein's Flawed Theory of Microbial Life Cycles and The Genius of His Powerful Isopathic Medications